Bone is the most common site of metastasis for breast cancer. Bone metastasis significantly affects both quality of life and survival of the breast cancer patient. Clinically, complications secondary to bone metastasis include pain, pathologic fractures, spinal cord compression, and hypercalcemia of malignancy. Because bone metastasis is extremely common in patients with metastatic breast cancer, clinical management of bone metastases is an important and challenging aspect of treatment in the metastatic setting. The skeleton is a metabolically active organ system that undergoes continuous remodeling throughout life.
10 ways to manage bone pain caused by cancer
Content - Health Encyclopedia - University of Rochester Medical Center
What is secondary breast cancer in the bone? Newly diagnosed or worried about a symptom? The bones 5. How is secondary breast cancer in the bone treated? Secondary breast cancer in the bone marrow 7. Palliative and supportive care 8.
Prognostic Factors in Patients with Metastatic Breast Cancer with Bone-Only Metastases
In the advanced stages of cancer, tumor cells may spread from the affected organ to different parts of the body, including the brain, liver, bones, etc. This process is called metastasis, and it occurs when cancer cells are released to the bloodstream, allowing them to freely invade other organs. The most common site of bone metastasis is the spine. Other sites include the hip, the upper leg, the upper arm, the ribs, and skull. The prognosis outcome of cancer that has spread to the bones varies according to many factors.
When breast cancer cells spread through the lymphatic system or blood vessels, they often take up residence in the bones, resulting in bone tumors, frequently called mets. The bone is a dynamic organ, constantly breaking down, building up and remodeling itself. This healthy cycle of growth is interrupted when cancer cells invade.